Fgf9^Aca12
Chemically induced Allele Detail

Summary

• Symbol: Fgf9^Aca12
• Name: fibroblast growth factor 9; ACMaster abnormality 12
• MGI ID: MGI:5293829
• Synonyms: Fgf9^Y162C
• Gene: Fgf9 Location: Chr14:58308543-58350311 bp, + strand Genetic Position: Chr14, 30.51 cM, cytoband D
• Alliance: Fgf9^Aca12 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced an A to G transition mutation resulting in an tyrosine to cysteine substitution at amino acid 162. (J:68708, J:176356)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf9 Mutation: 17 strains or lines available

References

• Original: J:176356 Puk O, et al., The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth. PLoS One. 2011;6(8):e23678
• All: 3 reference(s)