Tg(Fabp1-NTN1)6Mhln
Transgene Detail

Summary

• Symbol: Tg(Fabp1-NTN1)6Mhln
• Name: transgene insertion 6, Patrick Mehlen
• MGI ID: MGI:5317946
• Synonyms: c-Myc-tagged chick netrin-1, Tg6-netrin-1
• Transgene: Tg(Fabp1-NTN1)6Mhln Location: unknown
• Alliance: Tg(Fabp1-NTN1)6Mhln page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp1-NTN1)6Mhln expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  chicken	NTN1 (396389)

• Mutation details: This transgene employs the gut-directed Fabpl^{4x at -132} promoter cassette from the pTS4 expression vector to drive expression of a full-length cDNA encoding chicken netrin 1 (NTN1) with a C-terminal Myc epitope tag (EQKLISSEEDL). The promoter cassette contains nucleotides (nt) -596 through +21 of the rat fatty acid binding protein 1, liver (Fabp1) gene with an insertion at nt -132 -- just upstream of its endogenous position -- of four additional tandem copies of the 35-bp putative nuclear protein binding site, composed of a direct repeat of the sequence TTCTGNNTT separated by five nts, that resides at nts -172 to -133 of the Fabpl gene. (J:39591, J:92659)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 4 reference(s)