Tg(tetO/CMV-CFTR)TC35Clh
Transgene Detail

Summary

• Symbol: Tg(tetO/CMV-CFTR)TC35Clh
• Name: transgene insertion TC35, Clare Huxley
• MGI ID: MGI:5318248
• Synonyms: Tg(CMV-tetO-CFTR)TC35CH
• Transgene: Tg(tetO/CMV-CFTR)TC35Clh Location: unknown
• Alliance: Tg(tetO/CMV-CFTR)TC35Clh page

Transgene origin

• Strain of Origin: C57BL/6J x CBA/Ca

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: This transgene contains a cDNA encoding the human cystic fibrosis transmembrane conductance regulator (CFTR) cloned into plasmid pUHD.10-3 between the PhCMV*-1 tetracycline-inducible promoter -- which is composed of a heptamer of the 19-base pair direct repeat tetracycline operator (tetO) followed by the human cytomegalovirus (CMV) immediate early (IE) minimal promoter, extending from nucleotide (nt) -53 to nt +75 -- and the SV40 polyadenylation signal. (J:169366)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:169366 MouseBook^TM, Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013
• All: 1 reference(s)