Nr1i2^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Nr1i2^tm1.1Ics
• Name: nuclear receptor subfamily 1, group I, member 2; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:5433121
• Synonyms: PXR CM
• Gene: Nr1i2 Location: Chr16:38068711-38115211 bp, - strand Genetic Position: Chr16, 26.64 cM
• Alliance: Nr1i2^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186761
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 and 4 were flanked with a loxP site and a neomycin resistance cassette flanked by loxP and FRT sites. Recombination removed the selection cassette. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Nr1i2 Mutation: 35 strains or lines available

References

• Original: J:186761 Selloum M, Direct Data Submission. MGI Direct Data Submission. 2012
• All: 3 reference(s)