Spns2^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Spns2^{tm1b(KOMP)Wtsi}
• Name: SPNS lysolipid transporter 2, sphingosine-1-phosphate; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5442804
• Gene: Spns2 Location: Chr11:72342464-72380730 bp, - strand Genetic Position: Chr11, 44.31 cM
• Alliance: Spns2^{tm1b(KOMP)Wtsi} page
• IMPC: Spns2 gene page

Mutation origin

• Mutant Cell Line: EPD0090_5_B04
• Germline Transmission: Earliest citation of germline transmission: J:188933
• Parent Cell Line: JM8.N19 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Cre-mediated recombination removed the neo cassette and exon 3. (J:188933)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Spns2 Mutation: 31 strains or lines available

References

• Original: J:188933 Nijnik A, et al., The role of sphingosine-1-phosphate transporter Spns2 in immune system function. J Immunol. 2012 Jul 1;189(1):102-11
• All: 6 reference(s)