Tg(UBC-IghmAF6-78)68Nemz
Transgene Detail

Summary

• Symbol: Tg(UBC-IghmAF6-78)68Nemz
• Name: transgene insertion 68, David Nemazee
• MGI ID: MGI:5468133
• Synonyms: IgM^b-macroself
• Transgene: Tg(UBC-IghmAF6-78)68Nemz Location: unknown
• Alliance: Tg(UBC-IghmAF6-78)68Nemz page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(UBC-IghmAF6-78)68Nemz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ighm (MGI:96448)

• Mutation details: This mouse ubiquitously expresses sequences derived from hybridoma AF6-78 which is specific for IgM of the 'b' allotype. (J:193234)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:193234 Duong BH, et al., Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape. J Immunol. 2011 Dec 1;187(11):5596-605
• All: 3 reference(s)