Bcar1^tm1.1Homy
Targeted Allele Detail

Summary

• Symbol: Bcar1^tm1.1Homy
• Name: breast cancer anti-estrogen resistance 1; targeted mutation 1.1, Hiroaki Honda
• MGI ID: MGI:5495139
• Synonyms: Cas^deltaex2
• Gene: Bcar1 Location: Chr8:112437106-112470441 bp, - strand Genetic Position: Chr8, 57.98 cM, cytoband D3
• Alliance: Bcar1^tm1.1Homy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297113
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was floxed. Flp-mediated recombination removed the selection cassette. (J:297113)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bcar1 Mutation: 27 strains or lines available

References

• Original: J:297113 Tazaki T, et al., p130Cas, Crk-associated substrate plays essential roles in liver development by regulating sinusoidal endothelial cell fenestration. Hepatology. 2010;52(3):1089-99
• All: 1 reference(s)