Hprt1^{tm1(CMV-cre)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm1(CMV-cre)Wtsi}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:5496382
• Synonyms: CRET, Hprt
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm1(CMV-cre)Wtsi} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Hprt1^{tm1(CMV-cre)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  virus	CMV

• Mutation details: The targeting construct originally used to created the Hprt^{tm1(CMV-cre)Brd} allele was electroporated into JM8.F6 ES cells for homologous recombination. (J:75278)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CMV (virus) Summary of all recombinase alleles driven by CMV.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1279 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 6 reference(s)