Esrra^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Esrra^tm1.1Ics
• Name: estrogen related receptor, alpha; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:5496789
• Synonyms: ERRalpha^fl
• Gene: Esrra Location: Chr19:6888345-6899182 bp, - strand Genetic Position: Chr19, 5.08 cM
• Alliance: Esrra^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195925
• Parent Cell Line: P1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Exon 2 was floxed. Flp-mediated recombination removed the FRT-flanked selection cassette. (J:195925)

Generation of the conditional Esrra^tm1.1Ics allele

Expression

In Mice Carrying this Mutation:	208 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Esrra Mutation: 26 strains or lines available

References

• Original: J:195925 Gallet M, et al., Repression of osteoblast maturation by ERRalpha accounts for bone loss induced by estrogen deficiency. PLoS One. 2013;8(1):e54837
• All: 5 reference(s)