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Man2b2tm1b(KOMP)Wtsi
Targeted Allele Detail
Summary
Symbol: Man2b2tm1b(KOMP)Wtsi
Name: mannosidase 2, alpha B2; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5513801
Gene: Man2b2  Location: Chr5:36964265-36987997 bp, - strand  Genetic Position: Chr5, 19.26 cM, cytoband B2
Alliance: Man2b2tm1b(KOMP)Wtsi page
IMPC: Man2b2 gene page
Mutation
origin
Mutant Cell Line:  EPD0098_4_A08
Germline Transmission:  Earliest citation of germline transmission: J:200814
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsCre excision of MGI:4362174 tm1a allele removes the promoter-driven neo and critical exon(s) leaving behind the lacZ reporter (J:200814)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Man2b2 Mutation:  44 strains or lines available
References
Original:  J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory