Esrrb^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Esrrb^tm1.1Ics
• Name: estrogen related receptor, beta; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:5519215
• Synonyms: ERRbeta^L2
• Gene: Esrrb Location: Chr12:86407891-86568402 bp, + strand Genetic Position: Chr12, 40.49 cM
• Alliance: Esrrb^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201439
• Parent Cell Line: P1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A conditional mutation was generated by insertion of a loxP site upstream of exon 2 and a loxP- and FRT-flanked neomycin resistance cassette. Recombination removed the selection cassette.

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Esrrb Mutation: 211 strains or lines available

References

• Original: J:201439 Gan Z, et al., Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism. J Clin Invest. 2013 Jun 3;123(6):2564-75
• All: 2 reference(s)