Tg(IVL-Cela2a)55Hov
Transgene Detail

Summary

• Symbol: Tg(IVL-Cela2a)55Hov
• Name: transgene insertion 55, Alain Hovnanian
• MGI ID: MGI:5523057
• Synonyms: Tg-ELA2, Tg(INVO-Ela2aFLAG)55CPTP
• Transgene: Tg(IVL-Cela2a)55Hov Location: unknown
• Alliance: Tg(IVL-Cela2a)55Hov page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IVL-Cela2a)55Hov expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cela2a (MGI:95316)

• Mutation details: The murine chymotrypsin-like elastase family, member 2A cDNA fused with a FLAG tag was placed under the control of the human involucrin promoter. (J:158765)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:158765 Bonnart C, et al., Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing. J Clin Invest. 2010 Mar;120(3):871-82
• All: 1 reference(s)