Slc25a21^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Slc25a21^{tm1b(KOMP)Wtsi}
• Name: solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5548834
• Gene: Slc25a21 Location: Chr12:56759419-57244257 bp, - strand Genetic Position: Chr12, 24.54 cM
• Alliance: Slc25a21^{tm1b(KOMP)Wtsi} page
• IMPC: Slc25a21 gene page

Mutation origin

• Mutant Cell Line: EPD0085_1_D04
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Slc25a21^{tm1a(KOMP)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon 4 leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc25a21 Mutation: 26 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 2 reference(s)