Tg(PRNP-DNAJB2_ia)52aMec
Transgene Detail

Summary

• Symbol: Tg(PRNP-DNAJB2_ia)52aMec
• Name: transgene insertion 52a, Michael E Cheetham
• MGI ID: MGI:5613188
• Transgene: Tg(PRNP-DNAJB2_ia)52aMec Location: unknown
• Alliance: Tg(PRNP-DNAJB2_ia)52aMec page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(PRNP-DNAJB2_ia)52aMec expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PRNP (5621)

  Prnp	(MGI:97769)

• Human DNAJB2 isoform a is expressed under the control of a bovine PRNP promoter fragment. (J:217143)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:217143 Labbadia J, et al., Suppression of protein aggregation by chaperone modification of high molecular weight complexes. Brain. 2012 Apr;135(Pt 4):1180-96
• All: 1 reference(s)