Tg(Siglech-cre,-mCherry)#Spar
Transgene Detail

Summary

• Symbol: Tg(Siglech-cre,-mCherry)#Spar
• Name: transgene insertion, Tim Sparwasser
• MGI ID: MGI:5615447
• Synonyms: pDCre
• Transgene: Tg(Siglech-cre,-mCherry)#Spar Location: unknown
• Alliance: Tg(Siglech-cre,-mCherry)#Spar page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Siglech-cre,-mCherry)#Spar expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Siglech (MGI:2443256)

• Mutation details: This transgene was constructed from the RP24-396N13 BAC, containing the mouse sialic acid binding Ig-like lectin H (Siglech) gene, by replacing exon 1 of the gene with a cre-IRES-mCherry-p[A] construct. The promoter drives expression in plasmacytoid dendritic cells. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:214874)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Siglech (mouse) Summary of all recombinase alleles driven by Siglech. Alliance mouse Siglech gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:214874 Puttur F, et al., Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance. PLoS Pathog. 2013;9(9):e1003648
• All: 1 reference(s)