Tg(Pck1-GH1)9Rwh
Transgene Detail

Summary

• Symbol: Tg(Pck1-GH1)9Rwh
• Name: transgene insertion 9, Richard W Hanson
• MGI ID: MGI:5642300
• Synonyms: GH, PEPCK/bGH, PEPCK/bGH founder no. 9 line, Tg[0PCbGH]9, Tg(OPCGH)9, Tg[OPCKbGH]9
• Transgene: Tg(Pck1-GH1)9Rwh Location: unknown
• Alliance: Tg(Pck1-GH1)9Rwh page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pck1-GH1)9Rwh expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  cattle	GH1 (280804)	rat promoter, bovine gene

• Mutation details: This transgene contains the promoter/regulatory region (including cAMP and glucocorticoid regulatory elements) and the first 73 bp of exon 1of the rat phosphoenolpyruvate carboxykinase gene and expresses bovine growth hormone. (J:108869)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pck1-GH1)9Rwh

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:108869 McGrane MM, et al., Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice. J Biol Chem. 1988 Aug 15;263(23):11443-51
• All: 5 reference(s)