Bag6^tm1Mak
Targeted Allele Detail

Summary

• Symbol: Bag6^tm1Mak
• Name: BCL2-associated athanogene 6; targeted mutation 1, Tak Mak
• MGI ID: MGI:5645515
• Synonyms: Bat3^-
• Gene: Bag6 Location: Chr17:35354154-35366298 bp, + strand Genetic Position: Chr17, 18.59 cM
• Alliance: Bag6^tm1Mak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120375
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2-6 of the gene (containing sequences expressing the ubiquitin-like domain) were replaced with a cassette in which the neomycin resistance gene was under control of the PGK promoter (PGK-neo). (J:120375)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bag6 Mutation: 40 strains or lines available

References

• Original: J:120375 Sasaki T, et al., HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53. Genes Dev. 2007 Apr 1;21(7):848-61
• All: 1 reference(s)