About   Help   FAQ
Tg(Gfap-tTA)7Igta
Transgene Detail
Summary
Symbol: Tg(Gfap-tTA)7Igta
Name: transgene insertion 7, Ignacio Torres-Aleman
MGI ID: MGI:5645758
Synonyms: GFAP7, pGFAPtTA
Transgene: Tg(Gfap-tTA)7Igta  Location: unknown  
Alliance: Tg(Gfap-tTA)7Igta page
Transgene
origin
Strain of Origin:  C57BL/6 x SJL
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThis construct expresses tet-transactivator (tTA) under the astrocyte-specific GFAP promoter (pGFAP). A 1.8 kb genomic fragment of the murine Gfap promoter was placed upstream of a gene coding for tTA. (J:145253)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:145253 Fernandez AM, et al., Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals. J Neurosci. 2007 Aug 15;27(33):8745-56
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory