Trap1a^tm1Jvde
Targeted Allele Detail

Summary

• Symbol: Trap1a^tm1Jvde
• Name: tumor rejection antigen P1A; targeted mutation 1, Benoit Van den Eynd
• MGI ID: MGI:5645784
• Gene: Trap1a Location: ChrX:138234432-138238918 bp, + strand Genetic Position: ChrX, 61.35 cM
• Alliance: Trap1a^tm1Jvde page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180807
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Insertion of loxP sites, one into the Acc65I site located 15 bp upstream of the ATG in the first exon, and the other into the PstI site located in the first intron. (J:180807)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trap1a Mutation: 7 strains or lines available

References

• Original: J:180807 Huijbers IJ, et al., Minimal tolerance to a tumor antigen encoded by a cancer-germline gene. J Immunol. 2012 Jan 1;188(1):111-21
• All: 1 reference(s)