Retnla^tm1Gto
Targeted Allele Detail

Summary

• Symbol: Retnla^tm1Gto
• Name: resistin like alpha; targeted mutation 1, Goo Taeg Oh
• MGI ID: MGI:5707235
• Gene: Retnla Location: Chr16:48662972-48664824 bp, + strand Genetic Position: Chr16, 30.75 cM, cytoband B5
• Alliance: Retnla^tm1Gto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221255
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette replaced exons 1 through 4. The absence of protein expression was confirmed by western blot analysis on serum. (J:221255)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Retnla Mutation: 12 strains or lines available

References

• Original: J:221255 Lee MR, et al., The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice. Nat Commun. 2014;5:4410
• All: 2 reference(s)