Vezt^tm1.2Smc
Targeted Allele Detail

Summary

• Symbol: Vezt^tm1.2Smc
• Name: vezatin, adherens junctions transmembrane protein; targeted mutation 1.2, Marie C Simmler
• MGI ID: MGI:5749802
• Synonyms: bi-loxP vezt, Vezatin flox5, Vezt^fl, Vezt^flox5
• Gene: Vezt Location: Chr10:93797384-93871661 bp, - strand Genetic Position: Chr10, 48.72 cM
• Alliance: Vezt^tm1.2Smc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185644
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: This allele was derived from Vezt^tm1Smc by Cre recombinase excision of the loxP-flanked selection marker, leaving exon 5 intact and flanked by loxP sites. (J:121686, J:185644)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vezt Mutation: 36 strains or lines available

References

• Original: J:185644 Danglot L, et al., Vezatin Is Essential for Dendritic Spine Morphogenesis and Functional Synaptic Maturation. J Neurosci. 2012 Jun 27;32(26):9007-9022
• All: 3 reference(s)