Pla2g6tm1c(EUCOMM)Hmgu
Targeted Allele Detail
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Symbol: |
Pla2g6tm1c(EUCOMM)Hmgu |
Name: |
phospholipase A2, group VI; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5754997 |
Gene: |
Pla2g6 Location: Chr15:79170428-79212590 bp, - strand Genetic Position: Chr15, 37.7 cM
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Alliance: |
Pla2g6tm1c(EUCOMM)Hmgu page
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IMPC: |
Pla2g6 gene page |
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Mutant Cell Lines: |
HEPD0731_2_G05, HEPD0731_2_G07 |
Germline Transmission: |
Earliest citation of germline transmission:
J:101977
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The mutant allele has, from 5' to 3', an FRT site, an En2 splice acceptor cassette containing IRES, beta-galactosidase and polyA sequence, a loxP site, human beta-actin promoter, SV40 polyA, a second FRT site, and a second loxP site inserted upstream of exon 6. A third loxP-site is inserted downstream of exon 8. Flp-mediated recombination removed the FRT-flanked neo cassette and En2 splice acceptor leaving exons 6 through 8 floxed. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:157065)
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Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
5 reference(s) |
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