Crtc2^tm2Mmy
Targeted Allele Detail

Summary

• Symbol: Crtc2^tm2Mmy
• Name: CREB regulated transcription coactivator 2; targeted mutation 2, Marc R Montminy
• MGI ID: MGI:5755524
• Synonyms: CRTC2^flox
• Gene: Crtc2 Location: Chr3:90161475-90171432 bp, + strand Genetic Position: Chr3, 39.21 cM, cytoband F2
• Alliance: Crtc2^tm2Mmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224174
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 1 through 5 were floxed. (J:224174)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crtc2 Mutation: 27 strains or lines available

References

• Original: J:224174 Blanchet E, et al., Feedback inhibition of CREB signaling promotes beta cell dysfunction in insulin resistance. Cell Rep. 2015 Feb 24;10(7):1149-57
• All: 4 reference(s)