Fundc1^{tm1c(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Fundc1^{tm1c(KOMP)Wtsi}
• Name: FUN14 domain containing 1; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:5790641
• Gene: Fundc1 Location: ChrX:17422803-17438564 bp, - strand Genetic Position: ChrX, 12.8 cM, cytoband A2
• Alliance: Fundc1^{tm1c(KOMP)Wtsi} page
• IMPC: Fundc1 gene page

Mutation origin

• Mutant Cell Line: EPD0029_4_F01
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_gt2
• Mutation details: Flp-mediated excision of the parental Fundc1^{tm1a(KOMP)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and the inserted lacZ reporter sequence, leaving behind the loxP-flanked critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fundc1 Mutation: 10 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 5 reference(s)