Tg(Acta2-GFP)1Pfk
Transgene Detail

Summary

• Symbol: Tg(Acta2-GFP)1Pfk
• Name: transgene insertion 1, Peter Kador
• MGI ID: MGI:5805225
• Synonyms: alphaSMA-GFP, SMAA-GFP
• Transgene: Tg(Acta2-GFP)1Pfk Location: unknown
• Alliance: Tg(Acta2-GFP)1Pfk page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The transgene contains the promoter region of the mouse actin, alpha 2, smooth muscle, aorta (Acta2) gene, including 1074 bp of 5' flanking region, the transcription start site, the 48-bp first exon, the ~2.5-kb first intron, and 15 bp of exon 2, driving expression of green fluorescent protein. Transgenic mice express GFP specifically in both vascular and nonvascular smooth muscle cells. (J:43053, J:191415)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:191415 Yokota T, et al., Bone marrow lacks a transplantable progenitor for smooth muscle type alpha-actin-expressing cells. Stem Cells. 2006 Jan;24(1):13-22
• All: 13 reference(s)