Per2^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Per2^M1Btlr
• Name: period circadian clock 2; mutation 1, Bruce Beutler
• MGI ID: MGI:5805980
• Synonyms: Kortiku, Per2^Kort
• Gene: Per2 Location: Chr1:91343704-91387046 bp, - strand Genetic Position: Chr1, 46.13 cM, cytoband C5
• Alliance: Per2^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 91,423,829 (v38) on chromosome 1, or base pair 35,574 in the GenBank genomic region NC_000067. The mutation corresponds to residue 3,128 in the NM_011066 mRNA sequence, in exon 19 of 23 total exons. The mutation results in substitution of leucine 985 with proline (L985P) in the protein. (J:264638)
• Inheritance: Semidominant

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Per2 Mutation: 71 strains or lines available

References

• Original: J:264638 de Groot M, et al., Mutagenetix entry for Kortiku. MGI Direct Data Submission. 2018
• All: 2 reference(s)