Hcrtr1^tm1Ywa
Targeted Allele Detail

Summary

• Symbol: Hcrtr1^tm1Ywa
• Name: hypocretin (orexin) receptor 1; targeted mutation 1, Masashi Yanagisawa
• MGI ID: MGI:5812323
• Synonyms: Ox1r^-
• Gene: Hcrtr1 Location: Chr4:130024010-130033152 bp, - strand Genetic Position: Chr4, 63.43 cM
• Alliance: Hcrtr1^tm1Ywa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201941
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Exon 1 of the Ox1r gene is disrupted by inserting a tau-LacZ cassette. (J:201746)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hcrtr1 Mutation: 32 strains or lines available

References

• Original: J:201941 Hondo M, et al., Histamine-1 receptor is not required as a downstream effector of orexin-2 receptor in maintenance of basal sleep/wake states. Acta Physiol (Oxf). 2010 Mar;198(3):287-94
• All: 11 reference(s)