Adcyap1^tm1.1Lowl
Targeted Allele Detail

Summary

• Symbol: Adcyap1^tm1.1Lowl
• Name: adenylate cyclase activating polypeptide 1; targeted mutation 1.1, Bradford B Lowell
• MGI ID: MGI:5819248
• Synonyms: Adcyap1^fl, Adcyap1^lox, PACAP^fl
• Gene: Adcyap1 Location: Chr17:93506448-93513967 bp, + strand Genetic Position: Chr17, 60.67 cM
• Alliance: Adcyap1^tm1.1Lowl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238084
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Two loxP sites flank the second exon. When recombined, a frameshift mutation is introduced, and is predicted to result in a truncated protein. (J:238084)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adcyap1 Mutation: 22 strains or lines available

References

• Original: J:238084 Keenan WT, et al., A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction. Elife. 2016 Sep 26;5:e15392
• All: 5 reference(s)