Tg(Tcrb-V6)#Lantz
Transgene Detail

Summary

• Symbol: Tg(Tcrb-V6)#Lantz
• Name: transgene insertion, Olivier Lantz
• MGI ID: MGI:5829578
• Synonyms: Vbeta6 TCRbeta Tg, Vbeta6 Tg
• Transgene: Tg(Tcrb-V6)#Lantz Location: unknown
• Alliance: Tg(Tcrb-V6)#Lantz page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The recombined T cell receptor beta variable region (Tcrb-V6) sequence of a mucosal associated invariant T (MAIT) cell T-T hybridoma (having the canonical invariant Tcra-V19-J33 rearrangement) was inserted into a TCRbeta shuttle vector, which was then injected into mouse oocytes. The Tcrb-J segment is not identified. (J:55844, J:90982, J:149748)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

Notes

# is used in this transgene's symbol because two transgenic mouse lines were analyzed, and they are not distinguished from one another. (J:149748)

References

• Original: J:149748 Martin E, et al., Stepwise development of MAIT cells in mouse and human. PLoS Biol. 2009 Mar 10;7(3):e54
• All: 3 reference(s)