Myo6^Tur
Chemically induced Allele Detail

Summary

• Symbol: Myo6^Tur
• Name: myosin VI; Turner
• MGI ID: MGI:5882958
• Synonyms: Tur
• Gene: Myo6 Location: Chr9:80072313-80219011 bp, + strand Genetic Position: Chr9, 43.98 cM
• Alliance: Myo6^Tur page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU treatment induced a 820A to T mutation in exon 8, resulting in an Asn200Ile substitution in the peptide encoded by this allele. This substitution affects an extremely well-conserved amino-acid residue. (J:240216)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo6 Mutation: 90 strains or lines available

Notes

Generated in a large-scale ENU mutagenesis project at the McLaughlin Research Institute.

References

• Original: J:240216 Wong EY, et al., A Novel ENU-Induced Mutation in Myo6 Causes Vestibular Dysfunction and Deafness. PLoS One. 2016;11(5):e0154984
• All: 1 reference(s)