Mrgprf^tm1Wet
Targeted Allele Detail

Summary

• Symbol: Mrgprf^tm1Wet
• Name: MAS-related GPR, member F; targeted mutation 1, Nina Wettschureck
• MGI ID: MGI:5925347
• Synonyms: Mrgprf^{tm107656a(L1_L2_Bact_P)}, Mrgprf^tm1a
• Gene: Mrgprf Location: Chr7:144854646-144863294 bp, + strand Genetic Position: Chr7, 89.05 cM
• Alliance: Mrgprf^tm1Wet page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246058
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector Mrgprf purchased from the KOMP Repository was used to generate this allele. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site inserted in intron 2. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 3. (J:246058)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrgprf Mutation: 11 strains or lines available

References

• Original: J:246058 Kaur H, et al., Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system. Nat Commun. 2017 Jun 16;8:15700
• All: 1 reference(s)