Lrp8tm7Her
Targeted Allele Detail
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Symbol: |
Lrp8tm7Her |
Name: |
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; targeted mutation 7, Joachim Herz |
MGI ID: |
MGI:6147668 |
Synonyms: |
Apoer2[delta16delta19] |
Gene: |
Lrp8 Location: Chr4:107659337-107734037 bp, + strand Genetic Position: Chr4, 50.18 cM, cytoband C7
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Alliance: |
Lrp8tm7Her page
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Germline Transmission: |
Earliest citation of germline transmission:
J:258165
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Parent Cell Line: |
SM1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Modified isoform(s)) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A targeting vector with the sequence for exon 16 deleted and containing exons 17-20 and a downstream loxP-flanked neomycin cassette was inserted into the locus such that the locus constitutively expressed transcript without exons 16 and 19.
(J:258165)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lrp8 Mutation: |
41 strains or lines available
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Original: |
J:258165 Wasser CR, et al., Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning. Sci Signal. 2014 Nov 25;7(353):ra113 |
All: |
1 reference(s) |
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