Ugt2b1^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Ugt2b1^{tm1b(KOMP)Wtsi}
• Name: UDP glucuronosyltransferase 2 family, polypeptide B1; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:6149900
• Gene: Ugt2b1 Location: Chr5:87064498-87074362 bp, - strand Genetic Position: Chr5, 43.56 cM
• Alliance: Ugt2b1^{tm1b(KOMP)Wtsi} page
• IMPC: Ugt2b1 gene page

Mutation origin

• Mutant Cell Line: EPD0075_1_C07
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Ugt2b1^{tm1a(KOMP)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ugt2b1 Mutation: 31 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 2 reference(s)