Cdkn1b^em1Jung
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdkn1b^em1Jung
• Name: cyclin dependent kinase inhibitor 1B; endonuclease-mediated mutation 1, Steffen Jung
• MGI ID: MGI:6149960
• Synonyms: Cdkn1b^{3'UTR delta}
• Gene: Cdkn1b Location: Chr6:134897364-134902476 bp, + strand Genetic Position: Chr6, 65.77 cM
• Alliance: Cdkn1b^em1Jung page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the 3' UTR including a 85bp of the miR-142-3p seed binding region. (J:246250)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdkn1b Mutation: 25 strains or lines available

References

• Original: J:246250 Mildner A, et al., MicroRNA-142 controls thymocyte proliferation. Eur J Immunol. 2017 Jul;47(7):1142-1152
• All: 1 reference(s)