Trpv1^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trpv1^em1Bcgen
• Name: transient receptor potential cation channel, subfamily V, member 1; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:6154888
• Gene: Trpv1 Location: Chr11:73125118-73152068 bp, + strand Genetic Position: Chr11, 45.25 cM, cytoband B3
• Alliance: Trpv1^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Talen mediated recombination deleted the sequence from exon 2 through exon 16. (J:261155)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpv1 Mutation: 59 strains or lines available

References

• Original: J:261155 Huang M, et al., Capsaicin protects cortical neurons against ischemia/reperfusion injury via down-regulating NMDA receptors. Exp Neurol. 2017 Sep;295:66-76
• All: 1 reference(s)