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Setd1atm1b(EUCOMM)Wtsi
Targeted Allele Detail
Summary
Symbol: Setd1atm1b(EUCOMM)Wtsi
Name: SET domain containing 1A; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:6162235
Gene: Setd1a  Location: Chr7:127376561-127399294 bp, + strand  Genetic Position: Chr7, 69.73 cM
Alliance: Setd1atm1b(EUCOMM)Wtsi page
IMPC: Setd1a gene page
Mutation
origin
Mutant Cell Line:  EPD0027_4_H10
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_gt0
 
Mutation detailsCre-mediated excision of the parental Setd1atm1a(EUCOMM)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:204739)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Setd1a Mutation:  57 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory