Crlf3^{tm1c(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Crlf3^{tm1c(KOMP)Wtsi}
• Name: cytokine receptor-like factor 3; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:6164778
• Gene: Crlf3 Location: Chr11:79937319-79971817 bp, - strand Genetic Position: Chr11, 47.43 cM
• Alliance: Crlf3^{tm1c(KOMP)Wtsi} page
• IMPC: Crlf3 gene page

Mutation origin

• Mutant Cell Line: EPD0033_3_C11
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_gt0
• Mutation details: Flp-mediated excision of the parental Crlf3^{tm1a(KOMP)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and the inserted lacZ reporter sequence, leaving behind the loxP-flanked critical exon(s). Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:204739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Crlf3 Mutation: 51 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 1 reference(s)