Stxbp2^tm2Bdic
Targeted Allele Detail

Summary

• Symbol: Stxbp2^tm2Bdic
• Name: syntaxin binding protein 2; targeted mutation 2, Burton F Dickey
• MGI ID: MGI:6195193
• Synonyms: Munc18-2^F
• Gene: Stxbp2 Location: Chr8:3680955-3693644 bp, + strand Genetic Position: Chr8, 1.92 cM, cytoband A1
• Alliance: Stxbp2^tm2Bdic page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 1 was floxed via homologous recombination. (J:263883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stxbp2 Mutation: 36 strains or lines available

References

• Original: J:263883 Gutierrez BA, et al., Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem. 2018 May 11;293(19):7148-7159
• All: 1 reference(s)