Casz1^tm1Zel
Targeted Allele Detail

Summary

• Symbol: Casz1^tm1Zel
• Name: castor zinc finger 1; targeted mutation 1, Peggy Zelenka
• MGI ID: MGI:6197869
• Synonyms: Casz1^fl
• Gene: Casz1 Location: Chr4:148888886-149039346 bp, + strand Genetic Position: Chr4, 78.87 cM
• Alliance: Casz1^tm1Zel page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:264407
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 159 bp upstream of exon 9 and a loxP site and FRT flanked neo cassette were inserted 135 bp downstream of exon 11 via homologous recombination. (J:264407)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Casz1 Mutation: 345 strains or lines available

References

• Original: J:264407 Bhaskaran N, et al., Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity. Front Immunol. 2018;9:184
• All: 1 reference(s)