Tg(KRT14-RFP,-TK)4264Muth
Transgene Detail

Summary

• Symbol: Tg(KRT14-RFP,-TK)4264Muth
• Name: transgene insertion 4264, Senthil Muthuswamy
• MGI ID: MGI:6201424
• Synonyms: K14.tRPT
• Transgene: Tg(KRT14-RFP,-TK)4264Muth Location: unknown
• Alliance: Tg(KRT14-RFP,-TK)4264Muth page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The transgenic construct was designed with a human keratin 14 promoter driving co-expression of both a turbo red fluorescent protein (tRFP) and a suicide gene, herpes simplex virus (HSV) thymidine kinase (TK), separated by a P2A peptide plus a neomycin selection cassette. The neomycin cassette was later removed. tRFP is a fast-maturing destabilized red (orange) fluorescent protein. (J:264089)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:264089 Sonzogni O, et al., Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. PLoS Biol. 2018 Jun;16(6):e2004049
• All: 1 reference(s)