Htr6^em1(IMPC)Ics
Endonuclease-mediated Allele Detail

Summary

• Symbol: Htr6^em1(IMPC)Ics
• Name: 5-hydroxytryptamine (serotonin) receptor 6; endonuclease-mediated mutation 1, Mouse Clinical Institute
• MGI ID: MGI:6257771
• Synonyms: Htr6 KO
• Gene: Htr6 Location: Chr4:138788419-138802881 bp, - strand Genetic Position: Chr4, 70.57 cM
• Alliance: Htr6^em1(IMPC)Ics page
• IMPC: Htr6 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Institut Clinique de la Souris by injecting CAS9 RNA and 4 guide sequences ATAAGCTCCCCAGAGCCTACAGG, CCTCAACCCTAACACTAGACTGA, CCAGCTGAAGCACTAGGCCTAAC, CCCCTCCTAGGGGCTGGCAGGTC, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Htr6 Mutation: 27 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)