Htra4tm1.1Hohj
Targeted Allele Detail
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Symbol: |
Htra4tm1.1Hohj |
Name: |
HtrA serine peptidase 4; targeted mutation 1.1, Josephine Hoh |
MGI ID: |
MGI:6266862 |
Synonyms: |
HtrA4flox |
Gene: |
Htra4 Location: Chr8:25514945-25528978 bp, - strand Genetic Position: Chr8, 13.7 cM
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Alliance: |
Htra4tm1.1Hohj page
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Germline Transmission: |
Earliest citation of germline transmission:
J:266697
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 4. A FRT-flanked neomycin resistance cassette with a loxp site was inserted downstream of exon 5 and removed by flp-mediated recombination. A third loxP site was inserted downstream of exon 6.
(J:266697)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Htra4 Mutation: |
35 strains or lines available
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Original: |
J:266697 Liu J, et al., Generation and characterization of mice with a conditional null allele of the HtrA4 gene. Mol Med Rep. 2015 Nov;12(5):6768-74 |
All: |
2 reference(s) |
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