Ctnnb1^em1Nki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ctnnb1^em1Nki
• Name: catenin beta 1; endonuclease-mediated mutation 1, The Netherlands Cancer Institute
• MGI ID: MGI:6274675
• Gene: Ctnnb1 Location: Chr9:120762466-120789573 bp, + strand Genetic Position: Chr9, 72.19 cM
• Alliance: Ctnnb1^em1Nki page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting introduced an mTurquoise2 reporter gene at the ATG using guide RNA (5'-GCGTGGACAATGGCTACTCAAGG-3'). The mTq2/Ctnnb1 fusion protein is fully functional and localizes to the membrane, cytoplasm and nucleus. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ctnnb1 Mutation: 49 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)