Cav1^tm1Hshi
Targeted Allele Detail

Summary

• Symbol: Cav1^tm1Hshi
• Name: caveolin 1, caveolae protein; targeted mutation 1, Hiroaki Shimokawa
• MGI ID: MGI:6294244
• Synonyms: Cav-1^flox
• Gene: Cav1 Location: Chr6:17306387-17341323 bp, + strand Genetic Position: Chr6, 7.73 cM, cytoband A2
• Alliance: Cav1^tm1Hshi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:273561
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 3 was flanked by loxP sites. (J:273561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cav1 Mutation: 30 strains or lines available

References

• Original: J:273561 Saito H, et al., Important Role of Endothelial Caveolin-1 in the Protective Role of Endothelium-dependent Hyperpolarization Against Nitric Oxide-Mediated Nitrative Stress in Microcirculation in Mice. J Cardiovasc Pharmacol. 2018 Feb;71(2):113-126
• All: 2 reference(s)