Mzb1tm1Rug
Targeted Allele Detail
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Symbol: |
Mzb1tm1Rug |
Name: |
marginal zone B and B1 cell-specific protein 1; targeted mutation 1, Rudolf Grosschedl |
MGI ID: |
MGI:6294489 |
Synonyms: |
Mzb1fl;neo |
Gene: |
Mzb1 Location: Chr18:35780320-35782420 bp, - strand Genetic Position: Chr18, 19.19 cM
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Alliance: |
Mzb1tm1Rug page
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Germline Transmission: |
Earliest citation of germline transmission:
J:211639
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Parent Cell Line: |
D3 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette, loxP site, and splice acceptor and EGFP cassette were inserted into intron 4 via homologous recombination.
(J:211639)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mzb1 Mutation: |
9 strains or lines available
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Original: |
J:211639 Rosenbaum M, et al., MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress. Genes Dev. 2014 Jun 1;28(11):1165-78 |
All: |
1 reference(s) |
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