Tg(CAG-HIST1H2BB/mRFP,-Plk4/EYFP)39Dwc
Transgene Detail

Summary

• Symbol: Tg(CAG-HIST1H2BB/mRFP,-Plk4/EYFP)39Dwc
• Name: transgene insertion 39, Don W Cleveland
• MGI ID: MGI:6306860
• Synonyms: Plk4-OE
• Transgene: Tg(CAG-HIST1H2BB/mRFP,-Plk4/EYFP)39Dwc Location: unknown
• Alliance: Tg(CAG-HIST1H2BB/mRFP,-Plk4/EYFP)39Dwc page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(CAG-HIST1H2BB/mRFP,-Plk4/EYFP)39Dwc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Plk4 (MGI:101783)

• Mutation details: The transgenic construct contains in 5' to 3' order a chicken beta actin/rabbit beta-globin promoter, a loxP site, a histone H2B fused to monomeric RFP, a transcriptional STOP cassette, a loxP site, mouse Plk4 sequence fused to EYFP and a rabbit beta-globin polyA. (J:228145)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:228145 Vitre B, et al., Chronic centrosome amplification without tumorigenesis. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6321-30
• All: 1 reference(s)