Strn4^{tm1b(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Strn4^{tm1b(EUCOMM)Hmgu}
• Name: striatin, calmodulin binding protein 4; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6317368
• Gene: Strn4 Location: Chr7:16549814-16574856 bp, + strand Genetic Position: Chr7, 9.15 cM
• Alliance: Strn4^{tm1b(EUCOMM)Hmgu} page
• IMPC: Strn4 gene page

Mutation origin

• Mutant Cell Line: HEPD0511_5_D05
• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_gt0
• Mutation details: The L1L2_gt0 cassette was inserted at position 16555987 of Chromosome 7 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 16557275. The critical exon(s) is/are thus flanked by loxP sites. A null/knockout allele was created by cre recombinase expression in mice carrying the tm1a allele to remove the neo selection cassette and loxP-flanked critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:82809)

Expression

In Mice Carrying this Mutation:	116 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Strn4 Mutation: 34 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 3 reference(s)