Tg(tetO-GFP,-APOL1)#Susz
Transgene Detail
|
|
| Symbol: |
Tg(tetO-GFP,-APOL1)#Susz |
| Name: |
transgene insertion, Katalin Susztak |
| MGI ID: |
MGI:6331297 |
| Synonyms: |
TRE-APOL1-G0 |
| Transgene: |
Tg(tetO-GFP,-APOL1)#Susz Location: unknown
|
| Alliance: |
Tg(tetO-GFP,-APOL1)#Susz page
|
|
|
|
| Transgene Type: |
|
Transgenic (Humanized sequence, Inducible, Inserted expressed sequence, Reporter) |
| Inducer: |
|
doxycycline/tetracycline |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The human reference APOL1 variant G0 (no trypanolytic function in T. brucei rhodesiense) is under the control of the tetracycline responsive promoter element. The pound (#) sign is used when the line number is not specified or lines are pooled. The gene is only expressed in a tetracycline/doxycycline controllable manner when mice carrying this allele also carry a tTA or rtTA allele.
(J:251848)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:251848 Beckerman P, et al., Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice. Nat Med. 2017 Apr;23(4):429-438 |
| All: |
2 reference(s) |
|
Analysis Tools
