Mocos^em2(IMPC)Ics
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mocos^em2(IMPC)Ics
• Name: molybdenum cofactor sulfurase; endonuclease-mediated mutation 2, Mouse Clinical Institute
• MGI ID: MGI:6336104
• Synonyms: Mocos^-
• Gene: Mocos Location: Chr18:24786748-24834632 bp, + strand Genetic Position: Chr18, 13.18 cM
• Alliance: Mocos^em2(IMPC)Ics page
• IMPC: Mocos gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome-editing technology was used to generate a 243bp deletion including exon 3. (J:237616, J:336718)

Disease models

Expression

In Structures Affected by this Mutation:

15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mocos Mutation: 45 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)