Mir31^tm1.1Hwng
Targeted Allele Detail

Summary

• Symbol: Mir31^tm1.1Hwng
• Name: microRNA 31; targeted mutation 1.1, Honglin Wang
• MGI ID: MGI:6343491
• Synonyms: miR-31^fl
• Gene: Mir31 Location: Chr4:88828794-88828899 bp, - strand Genetic Position: Chr4, 42.05 cM
• Alliance: Mir31^tm1.1Hwng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224461
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The entire locis was flanked by the insertion of an frt-flanked PGK-neo cassette and a loxP site upstream of the gene, and a second loxP site downstream. The neomycin selectino cassette was removed via FLP-mediated recombination. (J:224461)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir31 Mutation: 4 strains or lines available

References

• Original: J:224461 Zhang L, et al., MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3. Nat Commun. 2015;6:7639
• All: 3 reference(s)